Hunan, China
Business Type:
Trading Company
Number of Employees:
9
Year of Establishment:
2018-03-14
Plant Area:
80 square meters
Average Lead Time:
Peak season lead time: within 15 workdays
Off season lead time: within 15 workdays
Sample Available

CAS 50-02-2, Dextelan, API Raw Material Dextelan manufacturer / supplier in China, offering API Raw Material Powder Dextelan 99% CAS 50-02-2, High Quality Local Anesthesia Drugs Raw White Powder of Lidocaine HCl / Lidocaine Hydrochloride 73-78-9, Ostarine Mk-2866/Mk 2866 Lean Muscle CAS: 841205-47-8 High Purity Sarms and so on.

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API Raw Material Powder Dextelan 99% CAS 50-02-2

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Basic Info

Model NO.
50-02-2
Transportation
EMS, Hkems, DHL, TNT, UPS
Deliverytime
Within 5 Days After Payment
Storage
Refrigerator
Port
Any Chinese Port
Application
Hormone Drugs
Assay
99%
Melting Point
211-214 °c(Lit.)
MW
362.46
Einecs
200-020-1
Density
1.0812 (Rough Estimate)
Trademark
YuCheng
Specification
BP/USP/GMP/BP/EP/CP/USP
Origin
China
HS Code
29372900

API Raw Material Powder Dextelan 99% CAS 50-02-2


Quick Details:

 
Product nameDextelan
Other nameDextelan/Dexone
CAS50-02-2
EINECS200-003-9
MFC22H29FO5
MW392.46
Form Powder
Assay>98%
AppearanceWhite to tan crystalline powder
UsageGlucocorticoid.
Density Density
refractive index76 ° (C=1, Dioxane)
Merck 14,4787

Product Name: Dextelan
Synonyms: dexa-sine;Dexason;Dexasone;dex-ide;dexinolon;dexinoral;Dexone;Dextelan
CAS: 50-02-2
MF: C22H29FO5
MW: 392.46
EINECS: 200-003-9
Product Categories: Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Steroid and Hormone;Pharmaceutical intermediate;API;MAXIDEX;Hormone Drugs;Mainly used for anti-inflammatory and allergy;Pharmaceuticals;Isotope Labeled Compounds;-;Pharmaceutical intermediates;pharmaceutical intermediate and medicine grade
Mol File: 50-02-2.mol
Melting point: 262-264 °C(lit.)
density: 1.1283 (estimate)
Refractive index: 76 ° (C=1, Dioxane)
storage temp.: 2-8°C
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.


Description:

Dextelan is an Anti-inflammatory glucocorticoid that is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide.

Dextelan induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cd k2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein in vitro.

Dextelan has been observed to induce apoptosis in human thymocytes and eosinophils, but inhibits apoptosis in neutrophils in vitro. Dexamethasone is an activator of IDO.

Dextelan Inhibits the expression of the inducible but not the constitutive nitric oxide synthase in vascular endothelial cells (IC50=5 nM).

Dextelan regulates T cell survival, growth, and differentiation.Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+-K+ pump. Has anti-inflammatory and anti-rheumatic properties. Induces apoptosis in human thymocytes. In general, 500-1000 nM of dexamethasone is sufficient to induce apoptosis following a 6-hour incubation at 37°C.

Application:

1. as an anti-inflammatory medication. Dextelan relieves inflammation in various parts of the body. it is used specifically to decrease swelling (edema), associated with tumors of the spine and brain, and to treat eye inflammation.

2. to treat or prevent allergic reactions.

3. as treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions.

4. as treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. 

5. to treat nausea and vomiting associated with some chemotherapy drugs.

6. used to stimulate appetite in cancer patients with severe appetite problems. 

7. used to replace steroids in conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands)..

COA:

items

standard

results

characteristics

a white or practically white, odorless, crystalline powder

conforms

specific rotation

75° (c=1, dioxane)

75°

purity

98% to 99.9%

99.2%

identification 

a. ir

conforms

b. uv

conforms

chromatographic impurity

total impurities ≤2.0%

any impurities ≤1.0%

conforms

residue on ignition

≤0.2%

    0.1%

loss on drying

≤0.5%

0.2%

organic volatile impurities

meets the requirements

conforms



API Raw Material Powder Dextelan 99% CAS 50-02-2


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Our Advancement:
A. We have stock so we can delivery quickly at the very day when receive the payment.
B. Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
C. High quality guarenteed, once any problem is found, the package would be reshipped for you.
D. Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air.The most professional forwarder
     would be recommanded for you.
E. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as                possible.Adhering to the principle of customer first conviction.we will provide the best and the most sincere services as possible as we can.o treat hyperthyroidism,obesity,or weight loss

Our Service and Shipping:

We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

 Delivery can be offered.

    - Utilizing your own freight-forwarder

    - FOB to a port in China

    - CIF to a port near you
Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.

Shipping by express (FedEx, UPS, DHL, EMS), by air; By ship.


Shipment will be arranged within 24 hours after receiving the payment;

Pictures of the package will be sent to you then along with the tracking number; Super discreet packaging, to ensure safe delivery, 99% successful delivery rate is ensured. Delivery time: All of the orders will be packed within 24 hours after we get the payment usually it takes about3~5work days for you to get the parcel. Payment method: Bank wire, Western union, Moneygram.

 

API Raw Material Powder Dextelan 99% CAS 50-02-2

API Raw Material Powder Dextelan 99% CAS 50-02-2
FRQ

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or  Moneygram

Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
    For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.

As a leading manufacturer of steroid raw materials  .and  Peptides 
We specialized in manufacturing high quality and reliable raw material 
which are widely used in the fields of food, health, cosmetics, pharmaceuticals, and Bodybuilding
 
we have formed a technology and management team that cooperate closely with some  overseas Labs  all speak highly of our safe shipping and goods .
please donot hesitate to contact us.


API Raw Material Powder Dextelan 99% CAS 50-02-2

API Raw Material Powder Dextelan 99% CAS 50-02-2
API Raw Material Powder Dextelan 99% CAS 50-02-2

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